Infectious DiseaseSepsisGeriatricsPulmonology

History of Present Illness

79-year-old male from an assisted living facility presenting to the ED with a fever and cough. He has a history of mild Alzheimer's disease. On arrival, he is tachycardic, hypotensive, and experiencing altered mental status (asking if it is dinnertime). A POLST form from his facility indicates he is to receive IV fluids and medications, but no intubation and no chest compressions (DNI/No CPR).

Patient Presentation
Elderly male patient presenting with confusion and fever. Atypical presentation of infection in the elderly often includes altered mental status (delirium) rather than just classic respiratory symptoms.

Emergency Department Course

Initial Evaluation & Intervention

00:26:44S01E01ED Room
HR 130, BP 90/60…Dr. Melissa King, Dr. Heather Collins

Patient arrival from an assisted living facility demonstrating signs of systemic inflammatory response syndrome (SIRS) and hypoperfusion.

Details

Medical Decision Making

The patient is an elderly male with fever, cough, tachycardia, and hypotension. Lung auscultation reveals coarse rhonchi, and imaging shows a right middle lobe infiltrate. This constellation of signs clearly indicates sepsis secondary to pneumonia. A 'Code Sepsis' is initiated to ensure rapid compliance with CMS guidelines (SEP-1 core measure bundle), which requires measuring a lactate level, obtaining blood cultures prior to administering broad-spectrum antibiotics, and administering a 30 cc/kg crystalloid fluid bolus for hypotension.

DDx:
SepsisCommunity-Acquired PneumoniaHealthcare-Associated PneumoniaAspiration PneumoniaViral Pneumonia/COVID-19

Diagnostics & Findings

  • Lung auscultation
  • Chest X-ray (revealing RML infiltrate)
  • Two sets of blood cultures ordered
  • Lactic acid ordered
Findings:
  • Coarse rhonchi on auscultation
  • Right middle lobe infiltrate
  • Fever of 102.0 F
  • Altered mental status/Confusion

Interventions

  • Review of POLST (DNI/No CPR confirmed)
  • Initial 500 cc normal saline bolus
  • 30 cc/kg normal saline ordered
  • Ceftriaxone 1g IV ordered
  • Azithromycin 500mg IV ordered

⮑ Outcome & Reassessment

Patient remains confused but compliant. Treatment protocol initiated pending lab results and response to fluid resuscitation.

Diagnoses & Disposition

Evolving Diagnoses

  • [S01E01]Right Middle Lobe Pneumonia
  • [S01E01]Sepsis

Current Disposition

Admitted/Undergoing Sepsis Protocol Treatment in the ED

Casebook Analysis

Episode Context

The case showcases the ED's morning rush of elderly patients arriving from nursing homes and assisted living facilities. It highlights the systematic nature of handling critical infections ('Code Sepsis') and sheds light on the bureaucratic pressure hospitals face regarding federal audits on sepsis bundle performance metrics.

Attending's Review

Medical Accuracy

The depiction of the 'Code Sepsis' protocol is highly accurate to modern emergency medicine standards. Drawing blood cultures before administering antibiotics, checking a lactic acid level, ordering 30 cc/kg of crystalloid for hypotension, and using Ceftriaxone plus Azithromycin to cover community-acquired or healthcare-associated pneumonia are all textbook, standard-of-care steps in the CMS SEP-1 core measure.

Clinical Pearls

Always check POLST/advanced directives early for patients arriving from assisted living or nursing homes before initiating invasive, life-sustaining procedures.

The 3-hour sepsis bundle requires lactate measurement, blood cultures prior to antibiotics, broad-spectrum antibiotics, and a 30 mL/kg crystalloid bolus for hypotension or a lactate >= 4 mmol/L.

Elderly patients with pneumonia often present with atypical symptoms, such as altered mental status or lethargy, which may be more prominent than the classic respiratory symptoms like cough.

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